Antifungal properties of various forms of sophorolipids

C - Chemistry – Metallurgy – 12 – P

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C12P 19/60 (2006.01) A61K 31/70 (2006.01) A61K 31/715 (2006.01) A61K 36/06 (2006.01) C12P 1/02 (2006.01)

Patent

CA 2592207

The preparation and use of 17-L-[(2'-O- ~-D-glucopyranosyl-p-D~glucopyranosyl)- oxy]-cis-9-octadecenoate, Lactonic and Open ring 17-L-[(2'-O-p~D- glucopyranosyl-~-D-glucopyranosyl)-oxy]-cis-9-octadecenoate, Methyl 17-L~[(2'- O-~-D-glucopyranosyl-~-D-glucopyranosyl)-oxy]-cis-9-octadecenoate, Ethyl 17-L- [(2'-O-~-D-glucopyranosyl-~-D-glucopyranosyl)-oxy]-cis-9-octadecenoate, Hexyl 17-L-[(2'-O-~-D-glucopyranosyl-p-D-glucopyranosyl)-oxy]-cis-9~octadecenoate, Ethyl 17-L-[(2'-O-~-D-glucopyranosyl-~-D-glucopy ranosyl)-oxy]~cis-9- octadecenoate-6"-acetate and Ethyl 17-L-[(2'-O-~-D-glucopyranosyl-~- D~gIucopyranosyl)-oxy]-cis-9-octadecenoate-6' ,6"-diacetate sophorolipids as antifungal agents.

L'invention se rapporte à la préparation et à l'utilisation de sophorolipides 17-L-[(2'-O-ß-D-glucopyranosyl-.beta.-D-glucopyranosyl)-oxy]-cis-9-octadécénoate, 17-L-[(2'-O-.beta.-D-glucopyranosyl-ß-D-glucopyranosyl)-oxy]-cis-9-octadécénoate de cycle ouvert et lactonique, 17-L-[(2'-O-ß-D-glucopyranosyl-ß-D-glucopyranosyl)-oxy]-cis-9-octadécénoate de méthyle, 17-L-[(2'-O-ß-D-glucopyranosyl-ß-D-glucopyranosyl)-oxy]-cis-9-octadécénoate d'éthyle, 17-L-[(2'-O-ß-D-glucopyranosyl-.beta.-D-glucopyranosyl)-oxy]-cis-9-octadécénoate d'hexyle, 17-L-[(2'-O-ß-D-glucopyranosyl-ß-D-glucopyranosyl)-oxy]-cis-9-octadécénoate-6"-acetate d'éthyle et 17-L-[(2'-O-ß-D-glucopyranosyl-ß-D-gIucopyranosyl)-oxy]-cis-9-octadécénoate-6',6"-diacétate d'éthyle en tant qu'agents antifongiques.

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