Antigen binding domains

Details Antigen binding domains Antigen binding domains

C - Chemistry, Metallurgy

07

K

C07K 16/00 (2006.01) A61K 39/395 (2006.01) C07K 16/18 (2006.01) C07K 16/40 (2006.01) C12N 1/21 (2006.01) C12N 15/63 (2006.01)

Patent

CA 2457636

A process for the production of an antigen specific antigen binding domain using a transformed host containing an expressible DNA sequence encoding the antigen specific antigen binding domain, wherein the antigen specific antigen binding domain is derived from a variable region of the immunoglobulin isotype NAR found in fish.

L'invention concerne un procédé d'élaboration de domaine de liaison d'antigène spécifique de l'antigène, consistant à utiliser un hôte transformé qui renferme une séquence d'ADN susceptible d'être exprimée et capable de coder ledit domaine, lequel est issu d'une région variable d'isotype d'immunoglobuline connu sous le nom de nouveau récepteur d'antigène (NAR), chez le poisson.

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