A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/385 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2533550
A compound for vaccination of an animal comprising (i) a moiety which selectively binds to a dendritic cell in the animal but which does not naturally occur in the animal and (ii) an antigen. Typically, the moiety which selectively binds as said binds to DC-SIGN. The moiety maybe HIV-1 gp 120. The compound of the invention may be used to vaccinate animals and, following vaccination, they may be distinguished from naturally infected animals.
L'invention concerne un composé de vaccination d'un animal contenant (i) une fraction qui se lie sélectivement à une cellule dendritique de l'animal mais n'apparaît pas naturellement chez l'animal, et (ii) un antigène. De manière générale, la fraction qui se lie sélectivement, comme susmentionné, se lie à DC-SIGN. Cette fraction peut être HIV-1 gp 120. On peut utiliser le composé de l'invention pour vacciner les animaux et, après vaccination, on peut distinguer ces animaux de ceux infectés par voie naturelle.
Borden Ladner Gervais Llp
The Royal Veterinary College
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