Antigen detection

G - Physics – 01 – N

Patent

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Details

G01N 33/80 (2006.01) G01N 33/50 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2602114

The present invention relates to methods of detecting specific cell surface antigens present in a sample of cells being tested and in particular blood group antigens, which methods do not employ the addition of extrinsic labels to detect said cell surface antigens. Typically detection is carried out using an intrinsic fluorescence capability of the cells being tested.

La présente invention concerne des méthodes de détection d'antigènes spécifiques de surface cellulaire présents dans un échantillon de cellules soumis à essai. Elle concerne en particulier des méthodes de détection d'antigènes des groupes sanguins. Les méthodes de l'invention n'emploient pas l'addition d'étiquettes extrinsèques pour détecter lesdits antigènes de surface cellulaire. Cette détection est généralement réalisée par l'exploitation d'une capacité de fluorescence intrinsèque des cellules soumises à essai.

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