Antigen of hybrid m protein and carrier for group a...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/62 (2006.01) A61K 39/09 (2006.01) A61K 39/40 (2006.01) C07K 14/245 (2006.01) C07K 14/315 (2006.01) C07K 19/00 (2006.01) C12N 15/31 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2123580

Recombinant hybrid streptococcal M protein antigens are provided which elicit protective antibodies against Group A streptococci and prevent rheumatic fever. Recombinant hybrid genes which encode the antigen are provided. Vaccine compositions and methods of administering the compositions are provided to elicit immunity against Group A streptococci.

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