Antigen-specific igg detection

G - Physics – 01 – N

Patent

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G01N 33/68 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2272369

The invention relates to a method for determining antigen-specific antibodies of immunoglobulin class G in the presence of immunoglobulins of class M in body fluids by incubation with at least two different receptors R1 and R2 and optionally additional receptors, wherein a bonding partner in monomer form is a substantial constituent of R2. The invention also relates to a reagent for determining an antigen-specific antibody of immunoglobulin class G and the use of bonding partners in monomer form for determining an antigen-specific antibody of immunoglobulin class G.

L'invention concerne un procédé pour la recherche d'anticorps spécifiques d'antigènes de la classe G d'immunoglobulines en présence d'immunoglobulines de la classe M dans des volumes humoraux par incubation avec au moins deux récepteurs différents R¿2? et R¿1? et éventuellement des récepteurs additionnels, un constituant essentiel de R¿2? étant un partenaire de liaison sous forme monomère, un réactif pour le dosage d'un anticorps spécifique d'antigène de la classe G d'immunoglobulines, ainsi que l'utilisation de partenaires de liaison sous forme monomère pour le dosage d'un anticorps spécifique d'antigène de la classe G d'immunoglobulines.

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