Antigen specific to meniere's disease and medical use thereof

Details Antigen specific to meniere's disease and medical use thereof Antigen specific to meniere's disease and medical use thereof

A - Human Necessities

61

K

A61K 39/00 (2006.01) A61K 35/12 (2006.01) C07H 15/10 (2006.01) C07K 16/18 (2006.01) G01N 33/53 (2006.01) G01N 33/564 (2006.01) G01N 33/68 (2006.01) G01N 33/92 (2006.01)

Patent

CA 2276080

An antigen specific to Ménière's disease and comprising a ganglioside having the sequence represented by NeuAc.alpha.2-3Gal.beta.1-4GlcNAc.beta.1- 3Gal.beta.1-4GlcNAc.beta.1-3Gal.beta.1-4Glc.beta.1-1Cer; a reagent kit containing the above specific antigen and used for detecting an antibody peculiar to Ménière's disease; an immunoassay for detecting an antibody peculiar to Ménière's disease by using the specific antigen; a reagent kit containing the above specific antigen and used for selectively isolating or removing an antibody peculiar to Ménière's disease; and a method for isolating or removing the above antibody.

Cette invention concerne un antigène spécifique contre la maladie de Ménière qui comprend un ganglioside dont la séquence est représentée par NeuAc .alpha.2-3Gal.beta.1-4GlcNAc.beta.1-3Gal.beta.1-4GlcNAc.beta.1-3Gal.beta.1-4Glc.beta.1-1Cer; un kit de réactif contenant l'antigène spécifique présenté ci-avant qu'on utilise pour détecter un anticorps propre à la maladie de Ménière; un dosage immunologique permettant de détecter un anticorps propre à la maladie de Ménière au moyen de l'antigène spécifique; un kit de réactif contenant l'antigène spécifique qu'on utilise pour isoler ou éliminer sélectivement un anticorps propre à la maladie de Ménière; et un procédé permettant d'isoler ou d'éliminer l'anticorps présenté ci-avant.

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