A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/39 (2006.01) A61K 9/127 (2006.01) A61K 9/00 (2006.01)
Patent
CA 2304824
The invention concerns an antigen vector, in particular a protein antigen, consisting of a dispersion of multilamellar vesicles within which said antigen is at least partially encapsulated, said vesicles consisting of two layers comprising at least a surfactant, said two layers being concentric and providing said vesicles with an onion-like structure. The invention also concerns compositions containing at least an antigen against which it is desired to produce antibodies, said antigen being partially encapsulated in such a vector. The invention further concerns the method for preparing said compositions.
L'invention concerne un vecteur d'antigène, en particulier d'antigène protéique, constitué d'une dispersion de vésicules multilamellaires au sein desquelles ledit antigène se trouve au moins partiellement encapsulé, lesdites vésicules étant constituées de bicouches comprenant au moins un agent tensioactif, lesdites bicouches étant concentriques et conférant auxdites vésicules une structure en oignon. Elle concerne également des compositions contenant au moins un antigène contre lequel on souhaite produire des anticorps, ledit antigène se trouvant partiellement encapsulé dans un tel vecteur. Elle concerne également le procédé de préparation de ces compositions.
Amedee Joelle
Delord Brigitte
Freund Olivier
Gaubert Sophie
Kaiserlian Dominique
Capsulis
Mccarthy Tetrault Llp
LandOfFree
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