Antigenic ck-18 compounds for therapy and diagnosis and...

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 15/12 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 7/06 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 16/30 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01) G01N 33/68 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2432883

The present invention provides methods and compositions for detecting, diagnosing, prognosing and monitoring the progress of CK-18-related cancers and malignancies and kits for use in said methods. Further provided are methods for screening to identify agonists and antagonists of cancer antigens associated with CK-18 related cancers and malignancies.

L'invention concerne des procédés et des compositions pour les opérations de détection, de diagnostic, de pronostic et de contrôle relatives à l'évolution des cancers et des affections malignes liées à la protéine CK-18, ainsi que des kits destinés à être utilisés pour la mise en oeuvre des procédés décrits. L'invention concerne par ailleurs des procédés de criblage permettant d'identifier des agonistes et des antagonistes vis-à-vis des antigènes associés aux cancers et aux affections malignes en question.

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