C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) A61K 39/106 (2006.01) C07K 14/205 (2006.01) C07K 16/12 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2288211
The present invention pertains to the characterization and isolation of newly discovered polypeptide antigens of H. pylori. Disclosed herein are cluster families of DNA replicas of portions of the genome of H. pylori encoding antigens which are highly immunogenic. Also disclosed are new antigenic proteins recovered from H. pylori. The invention also provides methods employing the above-described antigens.
La présente invention concerne la caractérisation et l'isolement d'antigènes polypeptidiques de H. pylori récemment découverts. L'invention a pour objet des familles groupées de répliques d'ADN de parties du génome d'antigènes codant H. pylori hautement immunogènes. L'invention porte également sur de nouvelles protéines antigéniques obtenues à partir de H. pylori. Cette invention concerne enfin des méthodes utilisant les antigènes décrits ci-dessus.
Chow Theresa P.
Fry Kirk E.
Lim Moon Y.
Mcatee C. P.
Genelabs Technologies Inc.
Gowling Lafleur Henderson Llp
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