Antigenic compositions and methods for their production and use

Details Antigenic compositions and methods for their production and use Antigenic compositions and methods for their production and use

G - Physics

01

N

167/37

G01N 33/569 (2006.01) C07K 14/205 (2006.01) G01N 33/543 (2006.01)

Patent

CA 1339067

Antigenic compositions are disclosed for use in diagnostic kits and the like fordetecting the presence of antibodies specific for Campylobacter pylori, bacteria often associated with the occurrence of Type B gastritis and peptic ulcer disease. Samples of bodily fluids, for instance, may be contacted with immobilized antigen which is then washed and tested for the occurrence of significant levels of antigen/antibody complex. Levels exceeding a predetermined positive threshold are indicative of antibodies to Campylobacter pylori in the sample tested. Kits employing the antigenic compositions of the invention preferably include means for detecting the antigen/antibody complex such as materials and reagents for conducting an enzyme-linked immunosorbent assay, Western blot technique, liposome-based assay or other known detection tests.

591107

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