Antigenic conjugates of conserved lipolysaccharides of gram...

A - Human Necessities – 61 – K

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A61K 39/385 (2006.01) A61K 39/02 (2006.01) A61K 39/095 (2006.01)

Patent

CA 2264970

Antigenic conjugates are provided which comprise a carrier protein covalently bonded to the conserved portion of a lipopolysaccharide of a gram negative bacteria, wherein said conserved portion of the lipopolysaccharide comprises the inner core and lipid A portions of said lipopolysaccharide, said conjugate eliciting a cross reactive immune response against heterologous strains of said gram negative bacteria.

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