Antigenic epitopes of interleukin-21, related antibodies and...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 7/00 (2006.01) A61K 39/395 (2006.01) C07K 16/24 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2587889

The present invention relates to antigenic epitopes of interleukin-21, related antibodies and their use in medical field, in particular for the treatment of immune-inflammatory diseases characterized by an enhanced production and/or activity of IL-21, such as for example chronic inflammatory bowel diseases (IBD), celiac disease and psoriasis.

La présente invention concerne des épitopes antigéniques de l'interleukine-21, des anticorps correspondants et leur utilisation dans le domaine médical, en particulier pour le traitement de maladies immuno-inflammatoires qui se caractérisent par une production et/ou une activité accrue de l'IL-21, telles que des maladies intestinales inflammatoires chroniques (IDB), la maladie coeliaque et le psoriasis.

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