Antigenic group b streptococcus type ii and type iii...

Details Antigenic group b streptococcus type ii and type iii... Antigenic group b streptococcus type ii and type iii...

C - Chemistry, Metallurgy

08

B

C08B 37/00 (2006.01) A61K 39/08 (2006.01) A61K 39/09 (2006.01) A61K 39/116 (2006.01) A61K 39/385 (2006.01) A61K 47/48 (2006.01) C07K 9/00 (2006.01) C07K 16/12 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2223080

The process for depolymerizing Group B Types II and III Streptococcus is disclosed which results in polysaccharide fragments having a reducing end suitable for conjugating to protein. Conjugate molecules, vaccines and their use to immunize mammals including humans are also disclosed.

Procédé de dépolymérisation de streptocoques de types II et III du groupe B, permettant d'obtenir des fragments de polysaccharides présentant une extrémité réductrice pouvant se conjuguer à la protéine. Les molécules conjuguées, les vaccins et leur utilisation pour l'immunisation de mammifères, y compris des êtres humains, sont également décrits.

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