Antiglaucoma compounds

A - Human Necessities – 61 – K

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A61K 31/22 (2006.01) A61K 31/215 (2006.01)

Patent

CA 1193198

ABSTRACT OF THE DISCLOSURE A composition for topical administration to reduce the intraocular pressure of a glaucomatous eye with little or no initial increase in the intraocular pressure, reduced contralateral effect, and reduced mydriasis. The composition comprises an aqueous solution having as active ingredient a compound of the formula Image and nontoxic, pharmaceutically acceptable acid salts thereof. The active ingredient is present in amount of about 0.001 to about 0.2 wt.% of the solution. The addition salt may be the hydrochloride or perchlorate.

415107

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