Antiglucocorticoids for the treatment of postpartum psychosis

A - Human Necessities – 61 – K

Patent

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A61K 31/56 (2006.01)

Patent

CA 2514966

This invention generally pertains to the field of psychiatry. In particular, this invention pertains to the discovery that agents which inhibit the binding of cortisol to its receptors can be used in methods for treating postpartum psychosis. Mifepristone, a potent specific glucocorticoid receptor antagonist, can be used in these methods. The invention also provides a kit for treating postpartum psychosis in a human including a glucocorticoid receptor antagonist and instructional material teaching the indications, dosage and schedule of administration of the glucocorticoid receptor antagonist.

Cette invention concerne, d'une manière générale, le domaine de la psychiatrie. En particulier, cette invention concerne la découverte que des agents qui inhibent la liaison du cortisol à ces récepteurs peut être utilisée dans des méthodes de traitement de la psychose postpartum. La mifepristone, un antagoniste du récepteur glucocorticoïde spécifique puissant, peut être utilisée dans ces méthodes. L'invention concerne également un kit de traitement de la psychose postpartum chez un sujet humain contenant un antagoniste du récepteur glucocorticoïde ainsi qu'un matériel d'instruction enseignant les indications, les posologies ainsi que la planification de l'administration de l'antagoniste du récepteur glucocorticoïde.

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