Antihistamine leukotriene combinations

Details Antihistamine leukotriene combinations Antihistamine leukotriene combinations

A - Human Necessities

61

K

A61K 31/55 (2006.01) A61K 31/381 (2006.01) A61K 31/404 (2006.01) A61K 31/41 (2006.01) A61K 31/4465 (2006.01) A61K 31/451 (2006.01) A61K 31/454 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) A61P 11/06 (2006.01) A61P 37/08 (2006.01)

Patent

CA 2337571

The invention relates to a pharmaceutical composition for the treatment of allergic rhinitis, vasomotor rhinitis, and allergic conjunctivitis, which comprises (a) a nonsedating antihistamine or a pharmaceutically acceptable salt thereof, (b) a leukotriene D4 antagonist, or a 5-lipoxygenase inhibitor, or a FLAP antagonist, or a pharmaceutically acceptable salt thereof, and (c) one or more of a conventional pharmaceutical vehicle, extender, and excipient, and to its use for manufacturing a composition for the treatment of allergic rhinitis, vasomotor rhinitis, and allergic conjunctivitis.

L'invention porte sur une composition pharmaceutique pour le traitement de la rhinite allergique, la rhinite vasomotrice, et la conjonctivite allergique, qui comprend (a) un antihistaminique non sédatif ou un de ses sels acceptables sur le plan pharmaceutique, (b) un antagoniste de leucotriènes D4, ou un inhibiteur de 5-lipoxygénase, ou un antagoniste de FLAP (protéine activatrice de 5-lipoxygénase), ou un de ses sels acceptables sur le plan pharmaceutique, et (c) un ou plusieurs véhicules pharmaceutiques courants, un succédané, un excipient, et d'usage dans la fabrication d'une composition pour le traitement de la rhinite allergique, la rhinite vasomotrice, et conjonctivite allergique.

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