Antihistaminic compounds, process for their preparation and...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/10 (2006.01) A61K 31/445 (2006.01)

Patent

CA 2118188

Antihistaminic compounds, process for their preparation and pharmaceutical compositions containing them Abstract The present invention relates to terfenadine derivatives of formula Image (I) where R1, which is in position 1 or 2 of the tetrazole ring, stands for H, or a linear or branched alkyl group containing from 1 to 6 carbon atoms; R2 and R3, different from one another, are selected between H and OH, and their pharmaceutically acceptable salts.

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