Antihypercholesterolemic bis-trifluoromethyl-substituted...

Details Antihypercholesterolemic bis-trifluoromethyl-substituted... Antihypercholesterolemic bis-trifluoromethyl-substituted...

C - Chemistry, Metallurgy

07

C

C07C 233/00 (2006.01) A61K 31/415 (2006.01) A61K 31/445 (2006.01) A61K 31/535 (2006.01) C07D 233/22 (2006.01) C07D 233/48 (2006.01) C07D 233/54 (2006.01) C07D 233/70 (2006.01) C07D 233/88 (2006.01) C07D 401/00 (2006.01) C07D 403/00 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/00 (2006.01)

Patent

CA 2084399

2084399 9119476 PCTABS00008 Provided are bis-trifluoromethyl-substituted imidazolines, as inhibitors of Acyl-CoA: Cholesterol Acyltransferase (ACAT), processes for their preparation, pharmaceutical compositions, and therapeutic methods for their use as antihypercholesterolemic or antiatherosclerotic agents.

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