Antihyperlipidemic and antiatherosclerotic trisubstituted...

Details Antihyperlipidemic and antiatherosclerotic trisubstituted... Antihyperlipidemic and antiatherosclerotic trisubstituted...

C - Chemistry, Metallurgy

07

C

167/207, 167/265

C07C 275/28 (2006.01) A61K 31/17 (2006.01) A61K 31/33 (2006.01) C07C 275/30 (2006.01)

Patent

CA 2010184

ABSTRACT Certain trisubstituted urea compounds as potent inhibitors of the enzyme acyl-CoA:cholesterol acyltransferase, their method of manufacture, pharmaceutical compositions containing such compounds as well as methods of inhibiting the interstitial absorption of cholesterol and lowering blood plasma cholesterol with such compounds as described.

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