Antihyperlipidemic and antiatherosclerotic urea compounds

Details Antihyperlipidemic and antiatherosclerotic urea compounds Antihyperlipidemic and antiatherosclerotic urea compounds

C - Chemistry, Metallurgy

07

C

C07C 275/40 (2006.01) C07C 275/28 (2006.01)

Patent

CA 2054209

Compounds useful as inhibitors of the enzyme aryl-coenzyme A: cholesterol acyltransferase having the following formula (I) wherein R is attached to the 3- or 4-position of the phenyl ring and is the group (a) wherein n is zero, one, or two, and R1 and R2 are straight or branched lower alkyl having from one to four carbon atoms or alkyl having from one to four carbon atoms wherein the terminal carbon is substituted with OR3 wherein R3 is hydrogen or alkyl having from one to four carbon atoms.

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