Antihypertensive agents

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 307/68 (2006.01) C07D 309/08 (2006.01)

Patent

CA 1057754

A B S T R A C T Described are antihypertensive agents selected from the class consisting of 2[4(tetrahydro-2-furoyl)- piperazino]-4-amino-6,7-dimethoxyquinazoline and 2-C4(tetra- hydropyran-2-carbonyl)-piperazinyl]-4-amino-6,7-dimethoxy- quinazoline, and pharmaceutically acceptable acid addition salts thereof. The compounds are highly water soluble and can be administered in time release form as well as parenterally, including intravenously.

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