Antihypertensive agents comprising 2- alkynyladenosines as...

C - Chemistry – Metallurgy – 07 – H

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C07H 19/067 (2006.01) A61K 31/70 (2006.01) C07H 19/16 (2006.01)

Patent

CA 1282065

ABSTRACT OF THE DISCLOSURE A 2-alkynyladenosine represented by general formula [I]: Image [I] wherein n is an integer of from 2 to 15, has been found to have excellent properties as an antihypertensive agent. On the basis of this finding, the present invention has provided an antihypertensive agent comprising an antihypertensive effective amount of a compound of the above formula [I] and a pharmaceutically acceptable carrier. The present invention also discloses a novel compound 2- alkynyladenosine of formula [I] shown above wherein n is 6 to 15.

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