Antihypertensive agents containing pyrazolopyrimidine...

Details Antihypertensive agents containing pyrazolopyrimidine... Antihypertensive agents containing pyrazolopyrimidine...

A - Human Necessities

61

K

A61K 31/505 (2006.01) A61K 31/519 (2006.01)

Patent

CA 2183834

Antihypertensive agents containing as its active ingredient the 4-amino-6-hydroxypyrazolo [3,4-d]pyrimidine(AHPP) or its derivatives represented by the general formula (I) below. (see Formula I) where R is hydrogen atom, alkyl group, alkoxyl group or aryl group. AHPP can be chemically synthesized by reaction of 3-amino-4-cyanopyrazole and urea. The antihypertensive agents of the present invention show a mild and reliable blood pressure lowering activity, and have different mode of action from the currently available antihypertensive agents.

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