A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/206
A61K 31/77 (2006.01) A61K 31/765 (2006.01) C08G 65/30 (2006.01)
Patent
CA 1314221
"ANTIINFECTIVE COMPOSITION CONTAINING NON-IONIC SURFACTANT" Abstract of the Invention The present invention comprises a compound and use which inhibits the growth of mycobacteria and comprises a method of treating humans or animals with the compound. The present invention also includes a composition useful for treating bacterial infections comprising a mixture of a nonionic block copolymer and a conventional antibiotic. Several conventional antibiotics that can be used with the nonionic copolymer include, but are not limited to, refampin, isoniazid, ethambutol, gentamicin, tetracycline, and erythromycin. Further the present invention includes a method for treating a viral infection in a human or animal including infections caused by the HIV virus or virus strains related to the HIV virus. The present invention comprises a surface active copoly- mer and is preferably an ethylene oxide-propylene oxide condensation product with the following general formula: HO(O2H4O)b(C3H6O)a(C2H4O)bH wherein a is an integer such that the hydrophobe represented by (C3H6O) has a molecular weight of about 1200 to 4000, preferably about 1750 to 3500, and b is an integer such that the hydrophile portion represented by (C2H4O) constitutes approximately 10% to 50% by weight of the compound. In a Supplementary Disclosure, the molecular weight range is expanded to about 1200 to 5300 and preferably 1750 to 4500.
559454
Emory University
Finlayson & Singlehurst
LandOfFree
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