C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/04 (2006.01) A61K 31/415 (2006.01) A61K 31/44 (2006.01) A61K 31/47 (2006.01) A61K 31/535 (2006.01) A61P 19/02 (2006.01) C07D 221/00 (2006.01) C07D 233/00 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 405/14 (2006.01) C07D 413/00 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01) C07D 471/04 (2006.01)
Patent
CA 2427284
Compounds, compositions and methods that are useful in the treatment of inflammatory, immunoregulatory, metabolic and cell proliferative conditions or diseases are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of proteins involved in inflammation, metabolism and cell proliferation. The subject compounds contain fused carbocyclic or heterocyclic rings.
L'invention se rapporte à des composés, des compositions et des méthodes qui sont utiles pour le traitement des maladies ou des troubles inflammatoires, immunorégulateurs, métaboliques ou liés à une prolifération cellulaire. L'invention se rapporte en particulier à des composés qui modulent l'expression et/ou la fonction de protéine impliquée dans l'inflammation, le métabolisme et la prolifération cellulaire. Les composés en question contiennent des cycles accolés carbocycliques ou hétérocycliques.
Browner Michelle F.
Clark David L.
Cushing Timothy D.
Hao Xiaolin
Hawley Ronald C.
Amgen Inc.
F. Hoffmann-La Roche Ag
Fetherstonhaugh & Co.
Tularik Inc.
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