Antiinflammatory carbinoloimidazoles

A - Human Necessities – 61 – K

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A61K 31/415 (2006.01) C07D 521/00 (2006.01)

Patent

CA 1336964

Antiinflammatory carbinoloimiazoles are provided which have the formula: (I) Image or a pharmaceutically acceptable salt thereof, wherein R1 and R2 independently are H, F, Cl, Br, CH3, OE 3 or S(O)nR3 where n is 0, 1 or 2 and R3 is alkyl of 1-4 carbon atoms; R4 is H or alkyl of 1-4 carbon atoms with the proviso that R4 is H when m is 2 or 3; and m is 1 to 3. The carbinoloimidazoles are preferably administered as topical antiinflammatory compositions.

607915

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