Antiinflammatory composition for external use

A - Human Necessities – 61 – K

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A61K 31/54 (2006.01) A61K 9/70 (2006.01) A61K 47/10 (2006.01) A61K 47/18 (2006.01) A61K 47/32 (2006.01) A61K 47/38 (2006.01)

Patent

CA 1206418

TOPICAL ANTI-INFLAMMATORY COMPOSITIONS Abstract A novel formulation of piroxicam for dermatolo- gical administration is disclosed. Pharmaceutical compositions containing piroxicam, lower alkanols, water, carboxyvinyl polymer, polyhydric alcohols, alkanolamines and optionally film-forming agents are prepared, said compositions having a pH of from about, 6.5 to about 9Ø The novel formulation is charac- terized by excellent applicability on the skin, skin- permeability and good stability. The novel formulation, which is in gel ointment form, is as effective as orally administered piroxicam and is well suited for topical administration through skin for the treatment of various types of inflammatory conditions.

432288

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