Antilymphoma targeting agents with effector and affinity...

Details Antilymphoma targeting agents with effector and affinity... Antilymphoma targeting agents with effector and affinity...

A - Human Necessities

61

K

A61K 51/10 (2006.01) A61K 47/42 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2509103

A medical agent comprising a reagent conjugated to an anti-lymphoma antibody is disclosed, as well as a kit containing said medical agent, use of said medical agent, and a method for treatment of lymphoma. The reagent may comprise an effector, e.g. an antitumor agent or a diagnostic marker, and an affinity ligand enabling extracorporeal clearance of the agent. The three components are bound by a trifunctional linker.

L'invention concerne un agent médical comprenant un réactif conjugué à un anticorps anti-lymphome, un kit renfermant ledit agent médical, l'utilisation dudit agent médical, ainsi qu'une méthode de traitement du lymphome. Le réactif peut comprendre un effecteur, par exemple, un agent anti-tumeur ou un marqueur diagnostique, et un ligand d'affinité permettant d'éliminer de manière extracorporelle l'agent. Les trois composants sont liés au moyen d'un lieur trifonctionnel.

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