C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 513/14 (2006.01) A61K 31/00 (2006.01) A61K 31/395 (2006.01) A61K 31/4164 (2006.01) A61K 31/426 (2006.01) A61K 31/4436 (2006.01) A61K 31/4439 (2006.01) A61P 33/06 (2006.01) C07D 207/20 (2006.01) C07D 207/22 (2006.01) C07D 233/20 (2006.01) C07D 233/28 (2006.01) C07D 277/10 (2006.01) C07D 277/12 (2006.01) C07D 417/04 (2006.01) C07D 417/06 (2006.01) C07D 513/18 (2006.01)
Patent
CA 2344913
Composition, article of manufacture for and method of treating malaria in a human having an infestation of Plasmodium protozoans are described. The method comprises administering a therapeutically-effective amount of a compound of formula (I) or (IV), i.e. sufficient quantity to reduce the population of Plasmodium. The composition of the invention is a compound of formula (I) or (IV) with a pharmaceutical excipient. The article of manufacture is the composition in combination with labeling for treating malaria. The substituents are detailed in the specification.
L'invention concerne une composition, un article fabriqué et une méthode de traitement du paludisme chez un humain souffrant d'une infestation par des protozoaires de Plasmodium. La méthode consiste à administrer une quantité efficace sur le plan thérapeutique d'un composé de la formule (I) ou (IV), c.-à-d. une quantité suffisante pour réduire la population de Plasmodium. La composition selon l'invention est un composé de la formule (I) ou (IV) avec un excipient pharmaceutique. L'article fabriqué se constitue de la composition combinée à un marquage de traitement du paludisme. Les substituants sont présentés en détail dans la description.
Bergeron Raymond J.
Brittenham Gary M.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
The Trustees Of Columbia University In The City Of New York
University Of Florida Research Foundation Inc.
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