Antimanic phenoxymethylene bisphosphonate derivatives

C - Chemistry – Metallurgy – 07 – F

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C07F 9/38 (2006.01) A61K 31/66 (2006.01) C07F 9/40 (2006.01) C07F 9/547 (2006.01)

Patent

CA 2054520

T1086 ABSTRACT ANTIMANIC PHENOXYMETHYLENE BISPHOSPHONATE DERIVATIVES A class of substituted phenoxymethylene bisphosphonate derivatives inhibit the action of inositol monophosphatase enzymes and are therefore useful in the treatment and/or prevention of bipolar and nonbipolar depressive disorders, and psychotic disorders other than mania, without exhibiting the spectrum of severe side- effects customarily associated with lithium treatment.

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