Antimicrobial activity of the first cationic cluster of...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 14/79 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/40 (2006.01) A61K 51/08 (2006.01) A61P 31/00 (2006.01) A61P 31/04 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C12N 1/06 (2006.01) C12N 1/20 (2006.01)

Patent

CA 2388910

The present invention provides polypeptides related to human lactoferrin protein that have utility in a variety of therapeutic and prophylactic applications, including use as antimicrobial agents. The invention further provides pharmaceutical compositions containing these polypeptides and therapeutic methods using such compositions. Methods for detecting antimicrobial infections using the polypeptides are also provided.

La présente invention concerne des polypeptides associés à la lactoferrine humaine utilisés dans diverses applications thérapeutiques et prophylactiques, y compris comme agents antimicrobiens. L'invention concerne également des compositions pharmaceutiques contenant ces polypeptides, et des méthodes thérapeutiques dans lesquelles sont utilisées ces compositions. L'invention concerne enfin des méthodes de détection d'infections antimicrobiennes à l'aide de ces polypeptides.

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