Antimicrobial collagenous constructs

Details Antimicrobial collagenous constructs Antimicrobial collagenous constructs

A - Human Necessities

61

K

A61K 35/37 (2006.01)

Patent

CA 2626460

Bioengineered collagen constructs with antimicrobial properties are provided. The bioengineered collagen constructs comprise a sheet-like layer of purified collagenous tissue matrix derived from a tissue source, such as the tunica submucosa of small intestine or a processed intestinal collagen layer derived from the tunica submucosa of small intestine, treated with an antimicrobial agent. The constructs arc biocompatible. The present invention has a variety of applications, including wound dressing and surgical repair devices. Methods for treating a damaged or diseased soft tissue are provided. Methods for treating a wound in need of care and treatment are also disclosed.

La présente invention concerne des constructions collagéniques produites par bio-ingénierie et présentant des propriétés antimicrobiennes. Les constructions collagéniques produites par bio-ingénierie comprennent une couche en forme de feuille d'une matrice tissulaire collagénique purifiée dérivée d'une source tissulaire telle que la tunique sous-muqueuse de l'intestin grêle ou une couche de collagène intestinal traité dérivée de la tunique sous-muqueuse de l'intestin grêle, traitée par un agent antimicrobien. Les constructions sont biocompatibles. La présente invention comprend diverses applications, dont le pansage des blessures et des dispositifs de réparation chirurgicale. L'invention concerne également des procédés de traitement d'un tissu mou malade ou lésé, ainsi que des procédés de traitement d'une blessure devant être soignée et traitée.

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