Antimicrobial compositions and methods of use thereof

Details Antimicrobial compositions and methods of use thereof Antimicrobial compositions and methods of use thereof

A - Human Necessities

61

K

A61K 31/198 (2006.01) A61K 31/19 (2006.01) A61K 31/194 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2571501

The present invention is directed to compositions which are useful for reducing and/or preventing bacterial infection/superinfection. The compositions include at least two weak organic acids in an inert carrier vehicle and are delivered at a pH of about 2.5 to 4.5. The weak organic acids are preferably acetic acid, vinegar, citric acid or combinations thereof. The inert carrier vehicle is preferably an aqueous based carrier in a gel form utilizing CARBOPOL as a gelling agent. The compositions of the invention are particularly applicable for reducing and/or preventing bacterial infection/superinfection of wounds.

L'invention concerne des compositions qui sont utilisées pour réduire et/ou empêcher des infections / surinfections bactériennes. Les compositions comprennent au moins deux acides organiques faibles dans un véhicule porteur inerte et sont administrés à un pH compris entre 2,5 et 4,5. Les acides organiques faibles sont de préférence un acide acétique, du vinaigre, de l'acide citrique ou une de leurs combinaisons. Le véhicule support inerte est de préférence un support à base d'eau se présentant sous la forme d'un gel utilisant du CARBOPOL comme agent gélifiant. Les compositions de l'invention sont utilisées, en particulier, pour réduire et/ou empêcher l'infection / la surinfection bactériennes de blessures.

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