Antimicrobial compositions useful for medical applications

Details Antimicrobial compositions useful for medical applications Antimicrobial compositions useful for medical applications

A - Human Necessities

01

N

A01N 59/16 (2006.01) A01N 25/10 (2006.01) A01N 25/34 (2006.01) A46D 1/00 (2006.01) A61K 31/765 (2006.01) A61K 33/38 (2006.01) A61K 47/34 (2006.01) A61K 47/48 (2006.01) A61L 15/42 (2006.01) A61L 15/44 (2006.01) A61L 15/46 (2006.01) A61L 27/00 (2006.01) A61L 27/54 (2006.01) A61L 29/16 (2006.01) A61L 31/00 (2006.01) A61L 31/16 (2006.01)

Patent

CA 2108008

Antimicrobial metal-based compositions, which are photostable, non staining, and which are easily absorbed into lipophilic matrices, contain silver cations, complexed by acyclic polyether polymers through the formation of a "host-guest relationship" where the acyclic polyether is the "host" and the silver cation is the "guest", wherein stabilization of this "host-guest relationship" is accomplished through the use of excess halide anions. The compositions are useful for topical treatment of infections caused by bacteria, fungus and viruses in humans and animals and for treating medical devices and adhesives to impart infection-resistance.

Compositions antimicrobiennes à base de métaux, photostables, non salissantes et facilement absorbées par des matrices lipophiles, contenant des cations d'argent complexés par des polymères de polyéthers acycliques par l'intermédiaire de la formation d'une "relation hôte-invité" dans laquelle le polyéther acyclique est l'"hôte" et le cation d'argent l'"invité", la stabilisation de cette "relation hôte-invité" étant accomplie grâce à l'utilisation d'anions d'halogénure excédentaires. Lesdites compositions sont utiles pour le traitement topique d'infections causées par des bactéries, des champignons et des virus chez l'homme et l'animal et pour traiter des dispositifs et adhésifs médicaux en vue de leur conférer une protection antimicrobienne.

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