Antimicrobial compounds from bacillus subtilis for use...

C - Chemistry – Metallurgy – 12 – P

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C12P 1/04 (2006.01) C07G 99/00 (2009.01) A23K 1/16 (2006.01) A23K 1/18 (2006.01) A61K 35/38 (2006.01) A61K 35/74 (2006.01) A61P 1/00 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2503130

Antimicrobial compounds from Bacillus subtilis for use against animal and human pathogens. A novel strain of Bacillus subtilis was isolated from the gastrointestinal tract of poultry and was found to produce a factor or factors that have excellent inhibitory effects on Clostridium perfringens, Clostridium difficile, Campylobacter jejuni, Campylobacter coli, and Streptococcus pneumoniae. The factor(s) retain full viability and antimicrobial activity after heat treatment. The invention provides a method of treatment of pathogenic microorganisms including C. perfringens.

L'invention concerne des composés anti-microbiens issus de Bacillus subtilis et à utiliser contre des pathogènes animaux et humains. Une nouvelle souche de Bacillus subtilis a été isolée du tractus gastro-intestinal de la volaille et s'est avérée produire un facteur ou des facteurs possédant d'excellents effets inhibiteurs sur Clostridium perfringens, Clostridium difficile, Campylobacter jejuni, Campylobacter coli et Streptococcus pneumoniae. Les facteurs conservent une viabilité totale et une activité anti-microbienne après un traitement thermique. L'invention concerne également une méthode de traitement des micro-organismes pathogènes renfermant C. perfringens.

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