Antimicrobial constructs

Details Antimicrobial constructs Antimicrobial constructs

A - Human Necessities

01

N

A01N 25/10 (2006.01) A61L 2/16 (2006.01) C08G 65/32 (2006.01) C08K 13/08 (2006.01)

Patent

CA 2696996

The invention is based on the recognition that known antimicrobial compounds, such as nisin or other lantibiotics, can be made to form a long lasting antimicrobial surface coating by linking the peptide with a block polymer, such as PLURONIC? F108 or an end group activated polymer (EGAP) in a manner to form a flexible tether and/or entrap the peptide. The entrapped pep-tide provides antimicrobial action by early release from entrapment while the tethered peptide provides longer lasting antimicrobial protection. Antimicrobial gels and foams may be prepared using the antimicrobial peptide containing block copolymers.

L'invention concerne la reconnaissance que des composés antimicrobiens, tels que la nisine ou d'autres lantibiotiques, peuvent être amenés à former un revêtement de surface antimicrobien de longue durée en liant le peptide à un copolymère séquencé, tel que PLURONIC® F108 ou un polymère activé par groupe d'extrémité (EGAP) de manière à former un lien flexible et/ou piéger le peptide. Le peptide piégé confère une action antimicrobienne par une libération précoce par rapport au piégeage alors que le peptide lié assure une protection antimicrobienne de plus longue durée. Des gels et mousses antimicrobiens peuvent être préparés en utilisant le peptide antimicrobien contenant des copolymères séquencés.

Affiliated with

Also associated with

Rating

Antimicrobial constructs does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antimicrobial constructs, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antimicrobial constructs will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1890528