Antimicrobial oxazolidinones, process of their preparation,...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 413/10 (2006.01) A61K 31/422 (2006.01) A61P 31/04 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2492743

The present invention provides agents having high antimicrobial activity for preventing and treating infectious diseases. Thus, the present invention provides novel cyanoalkylpiperidinophenyl oxazolidinone derivatives having antimicrobial activity, favourable pharmacokinetic and safety profiles, processes for making the compounds, as well as antimicrobial compositions containing said derivatives as active ingredients and methods of treating microbial infections with the said derivatives.

L~invention concerne des agents possédant une activité anti-microbienne élevée permettant de prévenir et de traiter des maladies infectieuses. Par conséquent, l~invention concerne des nouveaux dérivés de cyanoalkylpiperidinophényle oxazolidinone possédant une activité anti-microbienne, des profils pharmacocinétique et de sûreté favorables, des procédés de prépararion de ces composés, ainsi que des compositions anti-microbiennes renfermant lesdits dérivés comme principes actifs et des méthodes de traitement d~infections microbiennes au moyen desdits dérivés.

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