Antimicrobial peptide, compositions containing same and uses...

Details Antimicrobial peptide, compositions containing same and uses... Antimicrobial peptide, compositions containing same and uses...

C - Chemistry, Metallurgy

12

N

167/103, 530/7.1

C12N 15/12 (2006.01) A01N 63/02 (2006.01) A61K 38/17 (2006.01) A61L 2/18 (2006.01) C07K 14/47 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1340379

This invention provided a purified polypeptide useful as an antimicrobial agent. This purified polypeptide has been derived from human granulocytes, and has a molecular weight of about 3,700 daltons and the N-terminal amino acid sequence val-eys-ser-eys-arg-leu- val-phe-cys-arg-arg-thr-glu-leu-arg-val-gly-asn-cys- leu-ilu-gly-gly-val-ser-phe-thr-thr-cys-cys-thr-arg- val. This invention also provides methods for producing this polypeptide, pharmaceutical compositions containing the polypeptide, and uses thereof.

600617

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