Antimicrobial protein

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 7/04 (2006.01) A61K 38/04 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/17 (2006.01) A61P 31/04 (2006.01) A61P 31/10 (2006.01) A61P 31/12 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2641064

The present invention provides improved antimicrobial compositions comprising peptide fragments of tammar wallaby milk proteins and analogs and derivatives thereof exemplified by the amino acid sequences of SEQ ID Nos: 1-40 and uses therefor in the treatment of a range of infections by bacteria and fungi. The antimicrobial compositions are particularly useful for broad spectrum applications, especially for the treatment of bacterial infections.

La présente invention concerne des compositions antimicrobiennes améliorées contenant des fragments peptidiques de protéines extraites du lait d'un wallaby de l'île d'Eugène, d'analogues et de dérivés de ces protéines, exemplifiés par les séquences d'acides aminés SEQ ID No :1 à SEQ ID No :40, et leur utilisation dans le traitement d'une gamme d'infections bactériennes et fongiques. Les compositions antimicrobiennes sont particulièrement utiles pour des applications à large spectre, notamment pour le traitement d'infections bactériennes.

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