Antimicrobial protein compositions and production therefor...

Details Antimicrobial protein compositions and production therefor... Antimicrobial protein compositions and production therefor...

C - Chemistry, Metallurgy

07

K

C07K 14/195 (2006.01) A61K 39/02 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2735175

Several bacterial species were isolated from marine segment obtained from seabed sediment at depths exceeding 1700 feet. At least four of the bacteria produced a compound that showed antibacterial activity against one or more multiple-drug--resistant (MDR) bacteria isolated from hospitals and climes. One isolate, SJCH-12, exhibited a broad range of activity against MDR strains tested, including methicillin resistant Staphylococcus aureus (MRSA).

Plusieurs espèces de bactéries ont été isolées à partir d'un sédiment marin provenant de sédiment de lit marin à des profondeurs dépassant 1700 pieds. Au moins quatre bactéries produisent un composé qui présente une activité antibactérienne contre une ou plusieurs bactéries multirésistantes (BMR) aux antibiotiques isolées dans des hôpitaux et des cliniques. Un isolat, SJCH-12, présente une large gamme d'activités contre les souches de BMR testées, notamment Staphylococcus aureus résistant à la méthicilline (SARM).

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