Antimicrobial proteins

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/29 (2006.01) A01H 5/00 (2006.01) A01H 5/10 (2006.01) A01N 37/18 (2006.01) A01N 37/46 (2006.01) C07K 4/10 (2006.01) C07K 7/08 (2006.01) C07K 14/415 (2006.01) C12N 15/82 (2006.01) A61K 38/00 (2006.01) A01N 65/00 (2006.01)

Patent

CA 2274730

A new family of antimicrobial proteins is described. Prototype proteins can be isolated from Macadamia integrifolia as well as other plant species. DNA encoding the protein is also described as well as DNA constructs which can be used to express the antimicrobial protein or to introduce the antimicrobial protein into a plant. Compositions comprising the antimicrobial proteins or the antimicrobial protein per se can be administered to plants or mammilian animals to combat microbial infestation.

On décrit une nouvelle famille de protéines antimicrobiennes. Des protéines prototypes peuvent être isolées de Macadamia integrifolia, ainsi que d'autres espèces végétales. L'ADN codant pour la protéine est également décrit, de même que des ADN de recombinaison qui peuvent être utilisés pour exprimer la protéine antimicrobienne ou pour introduire la protéine antimicrobienne dans une plante. On peut utiliser des compositions comprenant la protéines antimicrobienne ou la protéine antimicrobienne pure pour traiter des plantes ou des animaux mammifères, dans le but de combattre les proliférations microbiennes.

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