Antimicrobial quaternary pyrazole derivatives

Details Antimicrobial quaternary pyrazole derivatives Antimicrobial quaternary pyrazole derivatives

C - Chemistry, Metallurgy

07

D

167/10.2, 260/31

C07D 231/12 (2006.01) A01N 43/56 (2006.01) C07D 521/00 (2006.01)

Patent

CA 1172642

ABSTRACT OF THE DISCLOSURE Quaternary pyrazole derivatives are disclosed having the formula Image wherein R is an alkyl having from 10 to 18 carbons with at least 10 carbons in its longest chain; R1 is a member selected from the group consisting of lower alkyl, C3-C5 alkenyl, benzyl, nitrobenzyl, halobenzyl and dihalobenzyl; R2 is a member selected from the group consisting of hydrogen and methyl; and R3 is a member selected from the group consisting of hydrogen and methyl X is an anion. These quarternary compounds are effective antimicrobial agents and are particularly useful in combatting bacteria, yeasts and fungi.

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