Antimicrobial quinolones, their compositions and uses

Details Antimicrobial quinolones, their compositions and uses Antimicrobial quinolones, their compositions and uses

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) A61K 31/47 (2006.01) A61K 31/4725 (2006.01) A61P 31/00 (2006.01)

Patent

CA 2303389

This invention relates to novel antimicrobial compounds of formula (1) wherein X, R1, R3, R5, R6 and R8 are defined in the claims, and to their optical isomers, diastereomers or enantiomers, as well as pharmaceutically-acceptable salts, hydrates, and biohydrolyzable esters, amides and imides thereof, and to compositions and uses of such compounds. The invention also relates to compounds derived from these compounds having antimicrobial uses.

L'invention a trait à de nouveaux composés antimicrobiens représentés par la formule (1) dans laquelle X, R1, R3, R5, R6 et R8 sont tels que définis dans les revendications; à leurs isomères, diastéréomères ou énantiomères optiques, ainsi qu'à des sels, des hydrates, et leurs esters, amides et imides biohydrolysables pharmaceutiquement acceptables; à des compositions et à l'utilisation de ces composés. L'invention concerne également des composés dérivés de ces composés présentant des usages antimicrobiens.

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