A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/74 (2006.01) A61K 31/785 (2006.01)
Patent
CA 2638768
The present disclosure is directed to polymers having hydroxyl containing bioactive agents incorporated into the backbone of the polymer or attached thereto by pendant linkages. Hydroxyl containing bioactive agents which may be attached to these polymers include antimicrobial agents such as triclosan. The polymers may be utilized to form medical devices or coatings for such devices. The hydroxyl containing bioactive agent may be released from the polymer upon hydrolysis of the polymeric backbone or pendant linkage in vivo.
La présente invention concerne des polymères composés d'agents bioactifs contenant de l'hydroxyle qui sont incorporés dans le squelette du polymère ou fixés à celui-ci par des liaisons attenantes. Les agents bioactifs contenant de l'hydroxyle qui peuvent être fixés à ces polymères incluent les agents antimicrobiens tels que le triclosan. Les polymères peuvent être utilisés pour fabriquer des dispositifs médicaux ou des revêtements pour de tels dispositifs. Les agents bioactifs contenant de l'hydroxyle peuvent être libérés du polymère par hydrolyse du squelette polymérique ou de la liaison attenante in vivo.
Belcheva Nadya
Cuevas Brian
Kennedy John
Roby Mark
Stopek Joshua B.
Mcfadden Fincham
Tyco Healthcare Group Lp
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