Antimicrobial solutions

A - Human Necessities – 01 – N

Patent

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A01N 47/12 (2006.01) A01N 43/50 (2006.01)

Patent

CA 2324272

Improved liquid antimicrobial solutions useful as preservative additives to personal care preparations, particularly cosmetic formulations and the like, are provided which comprise 1,3-dimethylol-5,5- disubstituted hydantoin, liquid aromatic alcohol, and iodoalkynyl alkyl carbamate. A preferred antimicrobial solution can be prepared by producing the 1,3-dimethylol-5,5-disubstituted hydantoin in situ in the selected liquid aromatic alcohol and then adding to the resulting solution the previously prepared iodoalkynyl alkyl carbamate. The solutions are surprisingly water dispersible and display broad spectrum antimicrobial effectiveness, particularly antifungal effectiveness, at a relatively low usage concentration in a cosmetic medium.

L'invention concerne des solutions antimicrobiennes liquides améliorées, utilisées en tant qu'additifs de conservation ajoutés aux préparations d'hygiène et de beauté, notamment aux formulations cosmétiques et similaires. Elles contiennent de l'hydantoïne 1,3-diméthylol-5,5-disubstituée, un alcool aromatique liquide et du carbamate d'iodoalkynyl alkyle. De préférence, on fabrique une solution antimicrobienne en produisant l'hydantoïne 1,3-diméthylol-5,5-disubstituée in situ, dans l'alcool aromatique liquide sélectionné, et en ajoutant à la solution ainsi obtenue du carbamate d'iodoalkynyl alkyle préparé antérieurement. Les solutions ont une dispersabilité dans l'eau étonnamment élevée et présentent un large spectre d'efficacité antimicrobienne, en particulier sur le plan antifongique, et ce avec une concentration d'utilisation dans un support cosmétique assez peu élevée.

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