C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 311/92 (2006.01) A61P 31/04 (2006.01) C07C 39/23 (2006.01) C07C 65/19 (2006.01) C07C 69/16 (2006.01)
Patent
CA 2712283
The present invention relates to substrates comprising a surface to which a compound is immobilised, methods for immobilising said compounds to substrates and devices, particularly medical devices, comprising said substrates. Compounds may include antimicrobial and/or anti-inflammatory compounds wherein substrates may be used to coat devices prone to bacterial colonisation, including implantable medical devices such as replacement joints, urinary catheters, percutaneous access catheters, stents, as well as non-implantable devices such as contact lenses and masks and apparatus for breathing medical air or oxygen. The present invention, further, extends to compounds suitable for use in preparing such substrates.
La présente invention concerne des substrats dotés d'une surface sur laquelle un composé est immobilisé, ainsi que des méthodes d'immobilisation desdits composés sur les substrats et les dispositifs, en particulier des dispositifs médicaux, comprenant lesdits substrats. Les composés peuvent comprendre des composés antimicrobiens et/ou anti-inflammatoires dans lesquels les substrats peuvent servir à recouvrir des dispositifs sujets à colonisation bactérienne, notamment des dispositifs médicaux implantables tels que des articulations de remplacement, des cathéters urinaires, des cathéters à accès percutané, des stents, ainsi que des dispositifs non implantables tels que des lentilles de contact et des masques et des appareils permettant de respirer de l'air ou de l'oxygène médical. La présente invention porte aussi sur des composés pouvant être utilisés lors de la préparation de tels substrats.
Griesser Hans Joerg
Ndi Chi Pius
Semple Susan Jean
Ys Hardi
Bennett Jones Llp
University Of South Australia
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