Antimycotically active cyclopropyl-substituted...

Details Antimycotically active cyclopropyl-substituted... Antimycotically active cyclopropyl-substituted...

C - Chemistry, Metallurgy

07

D

167/233, 260/313

C07D 233/61 (2006.01) A61K 31/41 (2006.01) C07C 255/45 (2006.01) C07D 249/08 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2003213

Antimycotically active 1-cyano- and 1-carboxamidocyclopropylazolylmethylcarbinols have now been found of the formula (see fig. I) in which R1 - represents hydrogen or - represents alkyl or - represents alkylcarbonyl, R2 - represents cyano or - represents a group of the formula (see fig. II) R3 - represents phenyl which is optionally substituted by halogen, straight-chain or branched alkyl, alkoxy, alkylthio, halogenoalkyl, halogenoalkoxy or halo-genoalkylthio, or by phenyl or phenoxy which, in turn, may be substituted by halogen or alkyl having up to 6 carbon atoms, X - represents a nitrogen atom or the CH group, Y - represents a bond or - represents a group of the formula (see fig. III, IV) or -C~C- in which R4 and R5 are identical or different and denote hydrogen or alkyl and their pharmaceutically tolerated acid addition salts.

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