Antineoplastic combinations containing hki-272 and vinorelbine

Details Antineoplastic combinations containing hki-272 and vinorelbine Antineoplastic combinations containing hki-272 and vinorelbine

A - Human Necessities

61

K

A61K 31/437 (2006.01) A61K 31/4745 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2725598

A combination of HKI-272 compound and a vinorelbine compound in the treatment of a neoplasm is provided. Regimens, kits, and methods for treatment of neoplasm, including breast cancer including metastatic breast cancer, and lung cancer, using this combination, optionally in combination with other anti-neoplastic agents, or immune modulators are also described.

Linvention concerne une combinaison dun composé HKI-272 et dun composé vinorelbine dans le cadre du traitement dun néoplasme. Linvention concerne également des régimes, kits et procédés de traitement dun néoplasme, et notamment du cancer métastasique du sein et du cancer du poumon utilisant ladite combinaison, éventuellement en association avec dautres agents antinéoplasiques ou modulateurs immunitaires.

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