Antiopoietin-related growth factor

Details Antiopoietin-related growth factor Antiopoietin-related growth factor

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 35/76 (2006.01) A61K 38/00 (2006.01) A61K 38/18 (2006.01) A61K 48/00 (2006.01) A61P 17/02 (2006.01) A61P 43/00 (2006.01) C07K 14/485 (2006.01) C07K 14/515 (2006.01) C12N 1/15 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2480419

It is intended to provide a mouse autologous growth factor (AGF) of human NL8/NEW which has been publicly known. Because of having an effect of promoting the growth of epidermal cells, AGF is useful as a wound healing agent or a tissue regenerating agent. It is also shown that a transgenic mouse with forced expression of AGF in epidermal cells is usable as a psoriasis model animal.

L'invention concerne un facteur de croissance autologue (AGF) connu de NL8/NEW humain. Du fait qu'il présente un effet de promotion de facteur de croissance de cellules épidermiques, on utilise AGF comme agent de cicatrisation de blessure ou comme agent de régénération tissulaire. On a également découvert qu'une souris transgénique dont l'expression d'AGF est forcée dans des cellules épidermiques peut être utilisée comme animal modèle du psoriasis.

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